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Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling

Idiopathic pulmonary fibrosis (IPF) is characterized by progressive pulmonary scarring, decline in lung function, and often results in death within 3–5 five years after diagnosis. Fibroblast growth factor (FGF) signaling has been implicated in the pathogenesis of IPF; however, the mechanism through...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Guzy, Robert D., Li, Ling, Smith, Craig, Dorry, Samuel J., Koo, Hyun Young, Chen, Lin, Ornitz, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481550/
https://ncbi.nlm.nih.gov/pubmed/28487375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.791764
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