Effects of mexiletine on ATP sensitive K(+) channel of rat skeletal muscle fibres: a state dependent mechanism of action

Por Tricarico, Domenico, Barbieri, Mariagrazia, Franchini, Carlo, Tortorella, Vincenzo, Conte Camerino, Diana
Publicado em 1998

Increased hindrance on the chiral carbon atom of mexiletine enhances the block of rat skeletal muscle Na(+) channels in a model of myotonia induced by ATX

Por Desaphy, Jean-François, Camerino, Diana Conte, Franchini, Carlo, Lentini, Giovanni, Tortorella, Vincenzo, De Luca, Annamaria
Publicado em 1999

Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide

Por De Luca, Annamaria, De Bellis, Michela, Corbo, Filomena, Franchini, Carlo, Muraglia, Marilena, Catalano, Alessia, Carocci, Alessia, Conte Camerino, Diana
Publicado em 2012

Synthesis of Functionalized Arylaziridines as Potential Antimicrobial Agents

Por Giovine, Arianna, Muraglia, Marilena, Florio, Marco Antonio, Rosato, Antonio, Corbo, Filomena, Franchini, Carlo, Musio, Biagia, Degennaro, Leonardo, Luisi, Renzo
Publicado no Molecules (2014)

Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres

Por Carbonara, Roberta, Carocci, Alessia, Roussel, Julien, Crescenzo, Giuseppe, Buonavoglia, Canio, Franchini, Carlo, Lentini, Giovanni, Camerino, Diana Conte, Desaphy, Jean-François
Publicado no Front Pharmacol (2015)

Elucidation of the synergistic action of Mentha Piperita essential oil with common antimicrobials

Por Rosato, Antonio, Carocci, Alessia, Catalano, Alessia, Clodoveo, Maria Lisa, Franchini, Carlo, Corbo, Filomena, Carbonara, Giuseppe Gerardo, Carrieri, Antonio, Fracchiolla, Giuseppe
Publicado no PLoS One (2018)

Phthalimide Derivative Shows Anti-angiogenic Activity in a 3D Microfluidic Model and No Teratogenicity in Zebrafish Embryos

Por Mercurio, Annalisa, Sharples, Lucy, Corbo, Filomena, Franchini, Carlo, Vacca, Angelo, Catalano, Alessia, Carocci, Alessia, Kamm, Roger D., Pavesi, Andrea, Adriani, Giulia
Publicado no Front Pharmacol (2019)

Molecular Insights into the Local Anesthetic Receptor within Voltage-Gated Sodium Channels Using Hydroxylated Analogs of Mexiletine

Por Desaphy, Jean-François, Dipalma, Antonella, Costanza, Teresa, Carbonara, Roberta, Dinardo, Maria Maddalena, Catalano, Alessia, Carocci, Alessia, Lentini, Giovanni, Franchini, Carlo, Camerino, Diana Conte
Publicado em 2012

Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na(+) channels enhancing the antimyotonic activity in vivo

Por Talon, Sophie, De Luca, Annamaria, De Bellis, Michela, Desaphy, Jean-François, Lentini, Giovanni, Scilimati, Antonio, Corbo, Filomena, Franchini, Carlo, Tortorella, Paolo, Jockusch, Harald, Conte Camerino, Diana
Publicado em 2001

Combined Modifications of Mexiletine Pharmacophores for New Lead Blockers of Na(v)1.4 Channels

Por De Bellis, Michela, De Luca, Annamaria, Desaphy, Jean F., Carbonara, Roberta, Heiny, Judith A., Kennedy, Ann, Carocci, Alessia, Cavalluzzi, Maria M., Lentini, Giovanni, Franchini, Carlo, Conte Camerino, Diana
Publicado em 2013

Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity

Por De Bellis, Michela, Carbonara, Roberta, Roussel, Julien, Farinato, Alessandro, Massari, Ada, Pierno, Sabata, Muraglia, Marilena, Corbo, Filomena, Franchini, Carlo, Carratù, Maria Rosaria, De Luca, Annamaria, Conte Camerino, Diana, Desaphy, Jean-François
Publicado no Neuropharmacology (2017)

Effects of Sweet Cherry Polyphenols on Enhanced Osteoclastogenesis Associated With Childhood Obesity

Por Corbo, Filomena, Brunetti, Giacomina, Crupi, Pasquale, Bortolotti, Sara, Storlino, Giuseppina, Piacente, Laura, Carocci, Alessia, Catalano, Alessia, Milani, Gualtiero, Colaianni, Graziana, Colucci, Silvia, Grano, Maria, Franchini, Carlo, Clodoveo, Maria Lisa, D'Amato, Gabriele, Faienza, Maria Felicia
Publicado no Front Immunol (2019)