Effects of mexiletine on ATP sensitive K(+) channel of rat skeletal muscle fibres: a state dependent mechanism of action

1. The effects of mexiletine were evaluated on the ATP-sensitive K(+) channel (K(ATP)) of rat skeletal muscle fibres using patch clamp techniques. The effects of mexiletine were studied on macropatch currents 20 s (maximally activated), 8 min (early stage of rundown) and 15 min (late stage of rundow...

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Bibliographic Details
Main Authors: Tricarico, Domenico, Barbieri, Mariagrazia, Franchini, Carlo, Tortorella, Vincenzo, Conte Camerino, Diana
Format: Artigo
Language:Inglês
Published: 1998
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571021/
https://ncbi.nlm.nih.gov/pubmed/9831925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702117
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