Učitavanje...
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres
Voltage-gated sodium channels are known to play a pivotal role in perception and transmission of pain sensations. Gain-of-function mutations in the genes encoding the peripheral neuronal sodium channels, hNav1.7–1.9, cause human painful diseases. Thus while treatment of chronic pain remains an unmet...
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| Izdano u: | Front Pharmacol |
|---|---|
| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4513211/ https://ncbi.nlm.nih.gov/pubmed/26257653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00155 |
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