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longev healthspan » longer healthspan (Expandir a Pesquisa), mouse healthspan (Expandir a Pesquisa)
longev healthspan » longer healthspan (Expandir a Pesquisa), mouse healthspan (Expandir a Pesquisa)
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Por Brand, Martin D
Publicado em 2014
“... on contemporary mitochondrial biology, Longevity & Healthspan presents a thematic series of four reviews...”Publicado em 2014
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Por Bansal, Ankita, Zhu, Lihua J., Yen, Kelvin, Tissenbaum, Heidi A.
Publicado no Proc Natl Acad Sci U S A (2015)
“... healthspan. However, it is largely unknown whether we are extending the healthy time of life or simply...”Publicado no Proc Natl Acad Sci U S A (2015)
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Por Hofmann, Jeffrey W., Zhao, Xiaoai, De Cecco, Marco, Peterson, Abigail L., Pagliaroli, Luca, Manivannan, Jayameenakshi, Hubbard, Gene B., Ikeno, Yuji, Zhang, Yongqing, Feng, Bin, Li, Xiaxi, Serre, Thomas, Qi, Wenbo, Van Remmen, Holly, Miller, Richard A., Bath, Kevin G., de Cabo, Rafael, Xu, Haiyan, Neretti, Nicola, Sedivy, John M.
Publicado no Cell (2015)
“..., which is inversely correlated with longevity. We also observe changes in nutrient and energy sensing...”Publicado no Cell (2015)
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“... is the guardian of healthspan, protecting against many age-related diseases including cancer and neurodegeneration...”
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“...) produce remarkable extension of longevity in laboratory mice. Importantly, the long-lived GH-related...”
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Por Roberts, Megan N., Wallace, Marita A., Tomilov, Alexey A., Zhou, Zeyu, Marcotte, George R., Tran, Dianna, Perez, Gabriella, Gutierrez-Casado, Elena, Koike, Shinchiro, Knotts, Trina A., Imai, Denise M., Griffey, Stephen M., Kim, Kyoungmi, Hagopian, Kevork, Haj, Fawaz G., Baar, Keith, Cortopassi, Gino A., Ramsey, Jon J., Lopez-Dominguez, Jose Alberto
Publicado no Cell Metab (2017)
“...-dependent manner. This study demonstrates that a KD extends longevity and healthspan in mice....”Publicado no Cell Metab (2017)
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“... of longevity in the roundworm Caenorhabditis elegans. Studies have reported that HIF-1 can function as both a...”
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Assuntos:
“...Ageing and Consequences for Longevity...”
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Por Sujkowski, Alyson, Bazzell, Brian, Carpenter, Kylie, Arking, Robert, Wessells, Robert J
Publicado no Aging (Albany NY) (2015)
“... to gene expression changes during selective breeding for longevity. Microarrays indicate that 65% of gene...”Publicado no Aging (Albany NY) (2015)
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Por Leiser, Scott F., Miller, Hillary, Rossner, Ryan, Fletcher, Marissa, Leonard, Alison, Primitivo, Melissa, Rintala, Nicholas, Ramos, Fresnida J., Miller, Dana L., Kaeberlein, Matt
Publicado no Science (2015)
“...Stabilization of the hypoxia-inducible factor-1 (HIF-1) increases lifespan and healthspan...”Publicado no Science (2015)
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Por Gelino, Sara, Chang, Jessica T., Kumsta, Caroline, She, Xingyu, Davis, Andrew, Nguyen, Christian, Panowski, Siler, Hansen, Malene
Publicado no PLoS Genet (2016)
“... mechanism contributing to the conserved effect of DR on longevity is the cellular recycling process...”Publicado no PLoS Genet (2016)
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Por Wu, Ryan T., Cao, Lei, Mattson, Elliot, Witwer, Kenneth W., Cao, Jay, Zeng, Huawei, He, Xin, Combs, Gerald F., Cheng, Wen‐Hsing
Publicado no Aging Cell (2016)
“... and decouple healthspan and longevity....”Publicado no Aging Cell (2016)
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Por Gelino, Sara, Chang, Jessica T., Kumsta, Caroline, She, Xingyu, Davis, Andrew, Nguyen, Christian, Panowski, Siler, Hansen, Malene
Publicado no PLoS Genet (2016)
Obter o texto integralPublicado no PLoS Genet (2016)
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“... of an optimal healthspan. Without improving healthspan, prolonging longevity would have enormous negative...”
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“...The first link between sirtuins and longevity was made 15 years ago in yeast. These initial studies...”
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Por Dai, Dao-Fu, Chiao, Ying Ann, Marcinek, David J, Szeto, Hazel H, Rabinovitch, Peter S
Publicado em 2014
“... in healthspan of many vital organ systems. In this article we review the evidence supporting the role...”Publicado em 2014
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“...Several behavioral and pharmacological strategies improve longevity, which is indicative of delayed...”
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