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Sirtuins: Guardians of Mammalian Healthspan

The first link between sirtuins and longevity was made 15 years ago in yeast. These initial studies sparked efforts by many laboratories working in diverse model organisms to elucidate the relationships between sirtuins, lifespan, and age-associated dysfunction. Here we discuss the current understan...

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Detalhes bibliográficos
Main Authors: Giblin, William, Skinner, Mary E., Lombard, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077918/
https://ncbi.nlm.nih.gov/pubmed/24877878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2014.04.007
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