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Sirtuins as regulators of metabolism and healthspan
Since the beginning of the century, the mammalian sirtuin protein family (SIRT1–SIRT7), has received much attention for their regulatory role, mainly in metabolism and aging. Sirtuins act in different cellular compartments: they deacetylate histones and several transcriptional regulators in the nucl...
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| Publié dans: | Nat Rev Mol Cell Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872805/ https://ncbi.nlm.nih.gov/pubmed/22395773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3293 |
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