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NAD(+) metabolism, a therapeutic target for age-related metabolic disease

Nicotinamide adenine dinucleotide (NAD) is a central metabolic cofactor by virtue of its redox capacity, and as such regulates a wealth of metabolic transformations. However, the identification of the longevity protein Sir2, the founding member of the sirtuin protein family, as being NAD(+)-dependen...

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Bibliographic Details
Main Authors: Mouchiroud, Laurent, Houtkooper, Riekelt H., Auwerx, Johan
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858599/
https://ncbi.nlm.nih.gov/pubmed/23742622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2013.789479
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