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Exploring the therapeutic space around NAD(+)
NAD(+) is a central metabolite in the cell. Changes in NAD(+) abundance and the activity of NAD(+)-dependent enzymes, such as the sirtuins, are at the core of metabolic/mitochondrial diseases, such as obesity and diabetes, and of cancer and neurodegeneration. Here, we discuss how maintaining or rais...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The Rockefeller University Press
2012
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471225/ https://ncbi.nlm.nih.gov/pubmed/23071150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201207019 |
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