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Sirtuins as regulators of metabolism and healthspan
Since the beginning of the century, the mammalian sirtuin protein family (SIRT1–SIRT7), has received much attention for their regulatory role, mainly in metabolism and aging. Sirtuins act in different cellular compartments: they deacetylate histones and several transcriptional regulators in the nucl...
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| 出版年: | Nat Rev Mol Cell Biol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872805/ https://ncbi.nlm.nih.gov/pubmed/22395773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3293 |
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