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Sirtuins as regulators of metabolism and healthspan

Since the beginning of the century, the mammalian sirtuin protein family (SIRT1–SIRT7), has received much attention for their regulatory role, mainly in metabolism and aging. Sirtuins act in different cellular compartments: they deacetylate histones and several transcriptional regulators in the nucl...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Rev Mol Cell Biol
मुख्य लेखकों: Houtkooper, Riekelt H., Pirinen, Eija, Auwerx, Johan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872805/
https://ncbi.nlm.nih.gov/pubmed/22395773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3293
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