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Are sirtuins viable targets for improving healthspan and lifespan?

Although the increased lifespan of our populations illustrates the success of modern medicine, the risk of developing many diseases increases exponentially with old age. Caloric restriction is known to retard ageing and delay functional decline as well as the onset of disease in most organisms. Stud...

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Detalhes bibliográficos
Publicado no:Nat Rev Drug Discov
Main Authors: Baur, Joseph A., Ungvari, Zoltan, Minor, Robin K., Couteur, David G. Le, de Cabo, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684642/
https://ncbi.nlm.nih.gov/pubmed/22653216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3738
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