Resultados da pesquisa - (( j l compr can new ) OR ((( m tail complex cause non ) OR ( 3.5 nac company cars now ))))

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1

CSI: Cancer Signature Investigation: ERBB2 (HER2)-Activating Mutation and Amplification-Positive Breast Carcinoma Mimicking Lung Primary

CSI: Cancer Signature Investigation: ERBB2 (HER2)-Activating Mutation and Amplification-Positive Breast Carcinoma Mimicking Lung Primary

Por Shih, Jennifer, Bashir, Babar, Gustafson, Karen S., Andrake, Mark, Dunbrack, Roland L., Goldstein, Lori J., Boumber, Yanis
Publicado no J Natl Compr Canc Netw (2015)

“... of the workup, the tumor was analyzed by a 50-gene targeted mutation panel, which detected 3 somatic mutations...”
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2

A myosin-Va tail fragment sequesters dynein light chains leading to apoptosis in melanoma cells

A myosin-Va tail fragment sequesters dynein light chains leading to apoptosis in melanoma cells

Por Izidoro-Toledo, T C, Borges, A C, Araújo, D D, Leitão Mazzi, D P S, Nascimento, F O, Sousa, J F, Alves, C P, Paiva, A P B, Trindade, D M, Patussi, E V, Peixoto, P M, Kinnally, K W, Espreafico, E M
Publicado em 2013

“... demonstrated that overexpression of a myosin-Va medial tail fragment (MVaf) harboring the binding site for DLC2...”
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3

Discrimination between neuropeptide Y and peptide YY in the rat tail artery by the neuropeptide Y1-selective antagonist, BIBP 3226.

Discrimination between neuropeptide Y and peptide YY in the rat tail artery by the neuropeptide Y1-selective antagonist, BIBP 3226.

Por Gicquiaux, H., Tschöpl, M., Doods, H. N., Bucher, B.
Publicado em 1996

“... that elicited by NPY. 3. Increasing concentrations of BIBP 3226 caused a parallel and rightward shift in the NPY...”
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4

Regulation of Ku-DNA Association by Yku70 C-terminal Tail and SUMO Modification

Regulation of Ku-DNA Association by Yku70 C-terminal Tail and SUMO Modification

Por Hang, Lisa E., Lopez, Christopher R., Liu, Xianpeng, Williams, Jaime M., Chung, Inn, Wei, Lei, Bertuch, Alison A., Zhao, Xiaolan
Publicado em 2014

“...The Ku70-Ku80 ring complex encloses DNA ends to facilitate telomere maintenance and DNA break...”
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5

Molecular Basis for the Anchoring of Proto-Oncoprotein Nup98 to the Cytoplasmic Face of the Nuclear Pore Complex

Molecular Basis for the Anchoring of Proto-Oncoprotein Nup98 to the Cytoplasmic Face of the Nuclear Pore Complex

Por Stuwe, Tobias T., von Borzyskowski, Lennart Schada, Davenport, Andrew M., Hoelz, André
Publicado no J Mol Biol (2012)

“...-terminal tail fragment of Nup159. The Nup82 β propeller serves as a non-cooperative binding platform...”
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6

Altered Anesthetic Sensitivity of Mice Lacking Ndufs4, a Subunit of Mitochondrial Complex I

Altered Anesthetic Sensitivity of Mice Lacking Ndufs4, a Subunit of Mitochondrial Complex I

Por Quintana, Albert, Morgan, Philip G., Kruse, Shane E., Palmiter, Richard D., Sedensky, Margaret M.
Publicado em 2012

“... anesthesia. Findings in C. elegans and in children reveal that defects in mitochondrial complex I can cause...”
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7

MYO3A causes human dominant deafness and interacts with protocadherin 15-CD2 isoform

MYO3A causes human dominant deafness and interacts with protocadherin 15-CD2 isoform

Por Grati, M’hamed, Yan, Denise, Raval, Manmeet H., Walsh, Tom, Ma, Qi, Chakchouk, Imen, Kannan-Sundhari, Abhiraami, Mittal, Rahul, Masmoudi, Saber, Blanton, Susan H., Tekin, Mustafa, King, Mary-Claire, Yengo, Christopher M., Liu, Xue Zhong
Publicado no Hum Mutat (2016)

“... the interaction of MYO3A with the cytosolic tail of the integral tip-link protein protocadherin 15 (PCDH15), a...”
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8

A Distributed Network for Intensive Longitudinal Monitoring in Metastatic Triple-Negative Breast Cancer

A Distributed Network for Intensive Longitudinal Monitoring in Metastatic Triple-Negative Breast Cancer

Por Blau, C. Anthony, Ramirez, Arturo B., Blau, Sibel, Pritchard, Colin C., Dorschner, Michael O., Schmechel, Stephen C., Martins, Timothy J., Mahen, Elisabeth M., Burton, Kimberly A., Komashko, Vitalina M., Radenbaugh, Amie J., Dougherty, Katy, Thomas, Anju, Miller, Christopher P., Annis, James, Fromm, Jonathan R., Song, Chaozhong, Chang, Elizabeth, Howard, Kellie, Austin, Sharon, Schmidt, Rodney A., Linenberger, Michael L., Becker, Pamela S., Senecal, Francis M., Mecham, Brigham H., Lee, Su-In, Madan, Anup, Ronen, Roy, Dutkowski, Janusz, Heimfeld, Shelly, Wood, Brent L., Stilwell, Jackie L., Kaldjian, Eric P., Haussler, David, Zhu, Jingchun
Publicado no J Natl Compr Canc Netw (2016)

“... patient with cancer can generate high-resolution views of the natural history of cancer and suggest new...”
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9

Receptive field organization of `sustained' and `transient' retinal ganglion cells which subserve different functional roles

Receptive field organization of `sustained' and `transient' retinal ganglion cells which subserve different functional roles

Por Ikeda, Hisako, Wright, M. J.
Publicado em 1972

“... field. 3. The sensitivity gradients of `sustained' and `transient' cells show consistent differences...”
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10

Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs

Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs

Por Färber, Valentin, Erben, Esteban, Sharma, Sahil, Stoecklin, Georg, Clayton, Christine
Publicado em 2013

“...The degradation of most eukaryotic mRNAs is initiated by removal of the poly(A) tail, and the major...”
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11

Dynamic MRI evaluation of urethral hypermobility post radical prostatectomy

Dynamic MRI evaluation of urethral hypermobility post radical prostatectomy

Por Suskind, Anne M., DeLancey, John O. L., Hussain, Hero K., Montgomery, Jeffrey S., Latini, Jerilyn M., Cameron, Anne P.
Publicado em 2013

“...AIMS: One postulated cause of post prostatectomy incontinence is urethral and bladder neck...”
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12

Role of Molecular Determinants of Store-operated Ca(2+) Entry (Orai1, Phospholipase A2 Group 6, and STIM1) in Focal Adhesion Formation and Cell Migration

Role of Molecular Determinants of Store-operated Ca(2+) Entry (Orai1, Phospholipase A2 Group 6, and STIM1) in Focal Adhesion Formation and Cell Migration

Por Schäfer, Claudia, Rymarczyk, Grzegorz, Ding, Lai, Kirber, Michael T., Bolotina, Victoria M.
Publicado em 2012

“..., but the mechanism of their involvement in this complex process is unknown. This study presents a detailed...”
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13

Mutation of zebrafish dihydrolipoamide branched-chain transacylase E2 results in motor dysfunction and models maple syrup urine disease

Mutation of zebrafish dihydrolipoamide branched-chain transacylase E2 results in motor dysfunction and models maple syrup urine disease

Por Friedrich, Timo, Lambert, Aaron M., Masino, Mark A., Downes, Gerald B.
Publicado em 2012

“... enzyme complex, to generate the que phenotype. In humans, mutation of the DBT gene causes maple syrup...”
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14

Vaccinia virus egress mediated by virus protein A36 is reliant on the F12 protein

Vaccinia virus egress mediated by virus protein A36 is reliant on the F12 protein

Por Carpentier, David C. J., Van Loggerenberg, Alexander, Dieckmann, Nele M. G., Smith, Geoffrey L.
Publicado no J Gen Virol (2017)

“...-1, and three viral proteins, A36 and the F12/E2 complex, have been implicated in this process...”
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15

Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation

Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation

Por Wang, Kai, Edmondson, Andrew C., Li, Mingyao, Gao, Fan, Qasim, Atif N., Devaney, Joseph M., Burnett, Mary Susan, Waterworth, Dawn M., Mooser, Vincent, Grant, Struan F. A., Epstein, Stephen E., Reilly, Muredach P., Hakonarson, Hakon, Rader, Daniel J.
Publicado em 2011

“... of quantitative traits may be benefited from these approaches, by sampling from two extreme tails...”
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16

TNF-α stimulation inhibits siRNA-mediated RNA interference through a mechanism involving poly-(A) tail stabilization

TNF-α stimulation inhibits siRNA-mediated RNA interference through a mechanism involving poly-(A) tail stabilization

Por Mols, Johann, van den Berg, Arjen, Otsuka, Motoyuki, Zheng, Min, Chen, Jianming, Han, Jiahuai
Publicado em 2008

“... that this stabilization is not caused by modifying si20 and miR16 loading into Ago2 complexes, or mRNA targeting to Ago2...”
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17

The role of deadenylation in the degradation of unstable mRNAs in trypanosomes

The role of deadenylation in the degradation of unstable mRNAs in trypanosomes

Por Schwede, Angela, Manful, Theresa, Jha, Bhaskar Anand, Helbig, Claudia, Bercovich, Natalia, Stewart, Mhairi, Clayton, Christine
Publicado em 2009

“... of several constitutively-expressed or long-lived mRNAs is not affected by depletion of the 5′–3...”
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18

Characterization of a TUTase/RNase complex required for Drosophila gametogenesis

Characterization of a TUTase/RNase complex required for Drosophila gametogenesis

Por Lin, Ching-Jung, Wen, Jiayu, Bejarano, Fernando, Hu, Fuqu, Bortolamiol-Becet, Diane, Kan, Lijuan, Sanfilippo, Piero, Kondo, Shu, Lai, Eric C.
Publicado no RNA (2017)

“... RNAs may be preferentially affected by Dis3L2. Overall, our studies of a new tailing/trimming complex...”
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19

Genomic analysis and relatedness of P2-like phages of the Burkholderia cepacia complex

Genomic analysis and relatedness of P2-like phages of the Burkholderia cepacia complex

Por Lynch, Karlene H, Stothard, Paul, Dennis, Jonathan J
Publicado em 2010

“... (vB_BceM-KS5 or vB_BmuZ-ATCC 17616), KS14 (vB_BceM-KS14) and KL3 (vB_BamM-KL3 or vB_BceZ-CEP511). RESULTS...”
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20

Antagonistic actions of two human Pan3 isoforms on global mRNA turnover

Antagonistic actions of two human Pan3 isoforms on global mRNA turnover

Por Chen, Chyi-Ying A., Zhang, Yueqiang, Xiang, Yu, Han, Leng, Shyu, Ann-Bin
Publicado no RNA (2017)

“... causes profound and extensive changes in mRNA stability globally. These results reveal a new fundamental...”
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