Laddar...
A myosin-Va tail fragment sequesters dynein light chains leading to apoptosis in melanoma cells
Previous studies proposed that myosin-Va regulates apoptosis by sequestering pro-apoptotic Bmf to the actin cytoskeleton through dynein light chain-2 (DLC2). Adhesion loss or other cytoskeletal perturbations would unleash Bmf, allowing it to bind and inhibit pro-survival Bcl2 proteins. Here, we demo...
Sparad:
| Huvudupphovsmän: | , , , , , , , , , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group
2013
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3613824/ https://ncbi.nlm.nih.gov/pubmed/23519116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.45 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|