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The role of deadenylation in the degradation of unstable mRNAs in trypanosomes
Removal of the poly(A) tail is the first step in the degradation of many eukaryotic mRNAs. In metazoans and yeast, the Ccr4/Caf1/Not complex has the predominant deadenylase activity, while the Pan2/Pan3 complex may trim poly(A) tails to the correct size, or initiate deadenylation. In trypanosomes, t...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760810/ https://ncbi.nlm.nih.gov/pubmed/19596809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp571 |
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