Intrinsic and regulated properties of minimally edited trypanosome mRNAs

Most mitochondrial mRNAs in kinetoplastids require extensive uridine insertion/deletion editing to generate translatable open reading frames. Editing is specified by trans-acting gRNAs and involves a complex machinery including basal and accessory factors. Here, we utilize high-throughput sequencing...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Tylec, Brianna L, Simpson, Rachel M, Kirby, Laura E, Chen, Runpu, Sun, Yijun, Koslowsky, Donna J, Read, Laurie K
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
RNA and RNA-protein complexes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468165/
https://ncbi.nlm.nih.gov/pubmed/30698753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz012
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