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Role of Molecular Determinants of Store-operated Ca(2+) Entry (Orai1, Phospholipase A2 Group 6, and STIM1) in Focal Adhesion Formation and Cell Migration

Store-operated Ca(2+) entry and its major determinants are known to be important for cell migration, but the mechanism of their involvement in this complex process is unknown. This study presents a detailed characterization of distinct roles of Orai1, STIM1, and PLA2g6 in focal adhesion (FA) formati...

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Autori principali: Schäfer, Claudia, Rymarczyk, Grzegorz, Ding, Lai, Kirber, Michael T., Bolotina, Victoria M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504787/
https://ncbi.nlm.nih.gov/pubmed/23043102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.407155
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