Nanoscale patterning of STIM1 and Orai1 during store-operated Ca(2+) entry

Stromal interacting molecule (STIM) and Orai proteins constitute the core machinery of store-operated calcium entry. We used transmission and freeze–fracture electron microscopy to visualize STIM1 and Orai1 at endoplasmic reticulum (ER)–plasma membrane (PM) junctions in HEK 293 cells. Compared with...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Perni, Stefano, Dynes, Joseph L., Yeromin, Andriy V., Cahalan, Michael D., Franzini-Armstrong, Clara
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603497/
https://ncbi.nlm.nih.gov/pubmed/26351694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515606112
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