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Overexpression of Orai1 and STIM1 Proteins Alters Regulation of Store-operated Ca(2+) Entry by Endogenous Mediators

Orai1 and STIM1 have been identified as the main determinants of the store-operated Ca(2+) entry (SOCE). Their specific roles in SOCE and their molecular interactions have been studied extensively following heterologous overexpression or molecular knockdown and extrapolated to the endogenous process...

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Autors principals: Gwozdz, Tomasz, Dutko-Gwozdz, Joanna, Schafer, Claudia, Bolotina, Victoria M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391152/
https://ncbi.nlm.nih.gov/pubmed/22549787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356626
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