Resultados da pesquisa - (( j l chima can new ) OR ((( 5 tail complex causes non ) OR ( 3 nacl company cas show ))))*

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Probing the Role of Parasite-specific, Distant, Structural Regions on Communication and Catalysis in the Bifunctional Thymidylate Synthase- Dihydrofolate Reductase from Plasmodium...

Por Dasgupta, Tina, Anderson, Karen S.
Publicado em 2008

“... causes a 3-fold enhancement of the DHFR rate from ~14 s(−1) to ~40 s(−1). In summary, our results...”
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The polyadenosine RNA-binding protein ZC3H14 interacts with the THO complex and coordinately regulates the processing of neuronal transcripts

Por Morris, Kevin J, Corbett, Anita H
Publicado no Nucleic Acids Res (2018)

“... is ubiquitously expressed, mutation of the ZC3H14 gene causes a non-syndromic form of intellectual disability...”
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Structural and functional characterization of the PNKP–XRCC4–LigIV DNA repair complex

Por Aceytuno, R. Daniel, Piett, Cortt G., Havali-Shahriari, Zahra, Edwards, Ross A., Rey, Martial, Ye, Ruiqiong, Javed, Fatima, Fang, Shujuan, Mani, Rajam, Weinfeld, Michael, Hammel, Michal, Tainer, John A., Schriemer, David C., Lees-Miller, Susan P., Glover, J.N. Mark
Publicado no Nucleic Acids Res (2017)

“.... NHEJ relies on polynucleotide kinase/phosphatase (PNKP), which generates 5΄-phosphate/3΄-hydroxyl DNA...”
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An alanine expanded PABPN1 causes increased utilization of intronic polyadenylation sites

Por Abbassi-Daloii, Tooba, Yousefi, Soheil, de Klerk, Eleonora, Grossouw, Laurens, Riaz, Muhammad, ’t Hoen, Peter A. C., Raz, Vered
Publicado no NPJ Aging Mech Dis (2017)

“... poly-adenine tail. The polyadenylation site is recognized by a dynamic protein complex, among which...”
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Abstracts of the 24th Meeting of the European Study Group for Cell Proliferation (ESGCP): Organized by the Institute for Medical Informatics, Statistics and Epidemiology (IMISE), U...

Publicado no Cell Prolif (2002)

“... normal karyotype, 29 with an unfavourable karyotype (−5, 5q‐, −7, 7q‐, complex aberrations) and 34...”
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Analysis of MRE11's function in the 5′→3′ processing of DNA double-strand breaks

Por Liao, Shuren, Guay, Catherine, Toczylowski, Thomas, Yan, Hong
Publicado em 2012

“...The resection of DNA double-strand breaks (DSBs) into 3′ single-strand tails is the initiating step...”
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The role of deadenylation in the degradation of unstable mRNAs in trypanosomes

Por Schwede, Angela, Manful, Theresa, Jha, Bhaskar Anand, Helbig, Claudia, Bercovich, Natalia, Stewart, Mhairi, Clayton, Christine
Publicado em 2009

“.... In metazoans and yeast, the Ccr4/Caf1/Not complex has the predominant deadenylase activity, while the Pan2/Pan3...”
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Co-assembly of Viral Envelope Glycoproteins Regulates Their Polarized Sorting in Neurons

Por Mattera, Rafael, Farías, Ginny G., Mardones, Gonzalo A., Bonifacino, Juan S.
Publicado em 2014

“... cytosolic tail with the clathrin adaptor complex AP-1. Co-expression of NiV-G with NiV-F abolished...”
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Altered Anesthetic Sensitivity of Mice Lacking Ndufs4, a Subunit of Mitochondrial Complex I

Por Quintana, Albert, Morgan, Philip G., Kruse, Shane E., Palmiter, Richard D., Sedensky, Margaret M.
Publicado em 2012

“... anesthesia. Findings in C. elegans and in children reveal that defects in mitochondrial complex I can cause...”
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Interaction between nerve-related acetylcholine and bath applied agonists at the frog end-plate.

Por Feltz, A, Trautmann, A
Publicado em 1980

“...-plate. The conditioning agonist, CCh, can cause desensitization (reduction of the ACh test response...”
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Melanoma Inhibitory Activity (MIA) Is Able to Induce Vitiligo-Like Depigmentation in an in vivo Mouse Model by Direct Injection in the Tail

Por Matteo Bordignon, Roberto Luisetto, Maria Luisa Valente, Marny Fedrigo, Chiara Castellani, Annalisa Angelini, Mauro Alaibac
Publicado em 2020-08-01

“... in non-segmental vitiligo skin and seems to cause the detachment of melanocytes, consequently creating...”
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Regulation of Ku-DNA Association by Yku70 C-terminal Tail and SUMO Modification

Por Hang, Lisa E., Lopez, Christopher R., Liu, Xianpeng, Williams, Jaime M., Chung, Inn, Wei, Lei, Bertuch, Alison A., Zhao, Xiaolan
Publicado em 2014

“... telomeres, increased G overhang levels, and altered levels of non-homologous end joining. We also show...”
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Light-activation of the Archaerhodopsin H(+)-pump reverses age-dependent loss of vertebrate regeneration: sparking system-level controls in vivo

Por Adams, Dany Spencer, Tseng, Ai-Sun, Levin, Michael
Publicado em 2013

“... of the endogenous H(+)-V-ATPase pump. However, existing pharmacological and genetic methods allow neither non...”
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Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5

Por Uchikawa, Emiko, Lethier, Mathilde, Malet, Hélène, Brunel, Joanna, Gerlier, Denis, Cusack, Stephen
Publicado no Mol Cell (2016)

“...RIG-I and MDA5 sense virus-derived short 5′ppp blunt-ended or long dsRNA, respectively, causing...”
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MYO3A causes human dominant deafness and interacts with protocadherin 15-CD2 isoform

Por Grati, M’hamed, Yan, Denise, Raval, Manmeet H., Walsh, Tom, Ma, Qi, Chakchouk, Imen, Kannan-Sundhari, Abhiraami, Mittal, Rahul, Masmoudi, Saber, Blanton, Susan H., Tekin, Mustafa, King, Mary-Claire, Yengo, Christopher M., Liu, Xue Zhong
Publicado no Hum Mutat (2016)

“... from five hearing-impaired relatives revealed a single variant, p.Gly488Glu (rs145970949:G>A) in MYO3A...”
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Structural determinants of specific DNA-recognition by the THAP zinc finger

Por Campagne, Sébastien, Saurel, Olivier, Gervais, Virginie, Milon, Alain
Publicado em 2010

“... report here the first 3D structure of the complex formed by the DNA-binding domain of THAP1 and its...”
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S-nitrosylation of Surfactant Protein D as a modulator of pulmonary inflammation

Por Atochina-Vasserman, Elena N.
Publicado em 2011

“... lectins “collectins” that play a role in non-antibody-mediated innate immune responses [1]. The primary...”
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Involvement of Arabidopsis thaliana endoplasmic reticulum KDEL-tailed cysteine endopeptidase 1...

Por Höwing, Timo, Dann, Marcel, Hoefle, Caroline, Hückelhoven, Ralph, Gietl, Christine
Publicado no PLoS One (2017)

“... plants and the atcep1 atcpr5-2 double mutants harboring a non-functional reporter (P(CEP1)::pre-pro-3xHA...”
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A myosin-Va tail fragment sequesters dynein light chains leading to apoptosis in melanoma cells

Por Izidoro-Toledo, T C, Borges, A C, Araújo, D D, Leitão Mazzi, D P S, Nascimento, F O, Sousa, J F, Alves, C P, Paiva, A P B, Trindade, D M, Patussi, E V, Peixoto, P M, Kinnally, K W, Espreafico, E M
Publicado em 2013

“... demonstrated that overexpression of a myosin-Va medial tail fragment (MVaf) harboring the binding site for DLC2...”
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Contribution of ultrarare variants in mTOR pathway genes to sporadic focal epilepsies

Por Pippucci, Tommaso, Licchetta, Laura, Baldassari, Sara, Marconi, Caterina, De Luise, Monica, Myers, Candace, Nardi, Elena, Provini, Federica, Cameli, Cinzia, Minardi, Raffaella, Bacchelli, Elena, Giordano, Lucio, Crichiutti, Giovanni, d'Orsi, Giuseppe, Seri, Marco, Gasparre, Giuseppe, Mefford, Heather C., Tinuper, Paolo, Bisulli, Francesca
Publicado no Ann Clin Transl Neurol (2019)

“... in genes coding for the components of complexes regulating mechanistic Target Of Rapamycin (mTOR)complex 1...”
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