Exploiting DNA repair defects in triple negative breast cancer to improve cell killing

por Lee, Kevin J., Mann, Elise, Wright, Griffin, Piett, Cortt G., Nagel, Zachary D., Gassman, Natalie R.
Publicado en Ther Adv Med Oncol (2020)

Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer

por Lee, Kevin J., Piett, Cortt G., Andrews, Joel F., Mann, Elise, Nagel, Zachary D., Gassman, Natalie R.
Publicado en PLoS One (2019)

Sodium sulfide selectively induces oxidative stress, DNA damage, and mitochondrial dysfunction and radiosensitizes glioblastoma (GBM) cells.

por Xiao, Adam Y., Maynard, Matthew R., Piett, Cortt G., Nagel, Zachary D., Alexander, J. Steven, Kevil, Christopher G., Berridge, Michael V., Pattillo, Christopher B., Rosen, Lane R., Miriyala, Sumitra, Harrison, Lynn
Publicado en Redox Biol (2019)

The CHD6 chromatin remodeler is an oxidative DNA damage response factor

por Moore, Shaun, Berger, N. Daniel, Luijsterburg, Martijn S., Piett, Cortt G., Stanley, Fintan K. T., Schräder, Christoph U., Fang, Shujuan, Chan, Jennifer A., Schriemer, David C., Nagel, Zachary D., van Attikum, Haico, Goodarzi, Aaron A.
Publicado en Nat Commun (2019)

Paradoxical Role of AT-rich Interactive Domain 1A in Restraining Pancreatic Carcinogenesis

por Ferri-Borgogno, Sammy, Barui, Sugata, McGee, Amberly M., Griffiths, Tamara, Singh, Pankaj K., Piett, Cortt G., Ghosh, Bidyut, Bhattacharyya, Sanchari, Singhi, Aatur, Pradhan, Kith, Verma, Amit, Nagel, Zac, Maitra, Anirban, Gupta, Sonal
Publicado en Cancers (Basel) (2020)

Structural and functional characterization of the PNKP–XRCC4–LigIV DNA repair complex

por Aceytuno, R. Daniel, Piett, Cortt G., Havali-Shahriari, Zahra, Edwards, Ross A., Rey, Martial, Ye, Ruiqiong, Javed, Fatima, Fang, Shujuan, Mani, Rajam, Weinfeld, Michael, Hammel, Michal, Tainer, John A., Schriemer, David C., Lees-Miller, Susan P., Glover, J.N. Mark
Publicado en Nucleic Acids Res (2017)

WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers

por Chan, Edmond M., Shibue, Tsukasa, McFarland, James M., Gaeta, Benjamin, Ghandi, Mahmoud, Dumont, Nancy, Gonzalez, Alfredo, McPartlan, Justine S., Li, Tianxia, Zhang, Yanxi, Liu, Jie Bin, Lazaro, Jean-Bernard, Gu, Peili, Piett, Cortt G., Apffel, Annie, Ali, Syed O., Deasy, Rebecca, Keskula, Paula, Ng, Raymond W.S., Roberts, Emma A., Reznichenko, Elizaveta, Leung, Lisa, Alimova, Maria, Schenone, Monica, Islam, Mirazul, Maruvka, Yosef E., Liu, Yang, Roper, Jatin, Raghavan, Srivatsan, Giannakis, Marios, Tseng, Yuen-Yi, Nagel, Zachary D., D’Andrea, Alan, Root, David E., Boehm, Jesse S., Getz, Gad, Chang, Sandy, Golub, Todd R., Tsherniak, Aviad, Vazquez, Francisca, Bass, Adam J.
Publicado en Nature (2019)