Sodium sulfide selectively induces oxidative stress, DNA damage, and mitochondrial dysfunction and radiosensitizes glioblastoma (GBM) cells.

Glioblastoma (GBM) has a poor prognosis despite intensive treatment with surgery and chemoradiotherapy. Previous studies using dose-escalated radiotherapy have demonstrated improved survival; however, increased rates of radionecrosis have limited its use. Development of radiosensitizers could improv...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Xiao, Adam Y., Maynard, Matthew R., Piett, Cortt G., Nagel, Zachary D., Alexander, J. Steven, Kevil, Christopher G., Berridge, Michael V., Pattillo, Christopher B., Rosen, Lane R., Miriyala, Sumitra, Harrison, Lynn
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556549/
https://ncbi.nlm.nih.gov/pubmed/31176262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101220
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