An alanine expanded PABPN1 causes increased utilization of intronic polyadenylation sites

In eukaryote genomes, the polyadenylation site marks termination of mature RNA transcripts by a poly-adenine tail. The polyadenylation site is recognized by a dynamic protein complex, among which the poly-adenine-binding protein nuclear1 plays a key role. Reduced poly-adenine-binding protein nuclear...

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Detalhes bibliográficos
Publicado no:NPJ Aging Mech Dis
Main Authors: Abbassi-Daloii, Tooba, Yousefi, Soheil, de Klerk, Eleonora, Grossouw, Laurens, Riaz, Muhammad, ’t Hoen, Peter A. C., Raz, Vered
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445584/
https://ncbi.nlm.nih.gov/pubmed/28649424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41514-017-0007-x
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