An alanine expanded PABPN1 causes increased utilization of intronic polyadenylation sites

In eukaryote genomes, the polyadenylation site marks termination of mature RNA transcripts by a poly-adenine tail. The polyadenylation site is recognized by a dynamic protein complex, among which the poly-adenine-binding protein nuclear1 plays a key role. Reduced poly-adenine-binding protein nuclear...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:NPJ Aging Mech Dis
Autori principali: Abbassi-Daloii, Tooba, Yousefi, Soheil, de Klerk, Eleonora, Grossouw, Laurens, Riaz, Muhammad, ’t Hoen, Peter A. C., Raz, Vered
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445584/
https://ncbi.nlm.nih.gov/pubmed/28649424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41514-017-0007-x
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi