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The Transient Receptor Potential Channel TRPM8 Is Inhibited via the α2A Adrenoreceptor Signaling Pathway

Por Bavencoffe, Alexis, Gkika, Dimitra, Kondratskyi, Artem, Beck, Benjamin, Borowiec, Anne-Sophie, Bidaux, Gabriel, Busserolles, Jérôme, Eschalier, Alain, Shuba, Yaroslav, Skryma, Roman, Prevarskaya, Natalia
Publicado em 2010

“... the α2A-AR signaling cascade could constitute a new mechanism of modulation of thermosensation in both...”
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The A(3) adenosine receptor agonist CP-532,903 protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP sensitive potassium channel

Por Wan, Tina C., Ge, Zhi-Dong, Tampo, Akihito, Mio, Yasushi, Bienengraeber, Martin W., Tracey, W. Ross, Gross, Garrett J., Kwok, Wai-Meng, Auchampach, John A.
Publicado em 2007

“...We examined the cardioprotective profile of the new A(3) adenosine receptor (AR) agonist CP-532,903...”
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2′-Methoxy-6-methylflavone: a novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA(A) receptors

Por Karim, Nasiara, Curmi, John, Gavande, Navnath, Johnston, Graham AR, Hanrahan, Jane R, Tierney, M Louise, Chebib, Mary
Publicado em 2012

“... mg·kg(−1); i.p.) displayed anxiolytic-like effects in two unconditioned models of anxiety: the elevated...”
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Phosphorylation of the ryanodine receptor 2 at serine 2030 is required for a complete β-adrenergic response

Por Potenza, Duilio M., Janicek, Radoslav, Fernandez-Tenorio, Miguel, Camors, Emmanuel, Ramos-Mondragón, Roberto, Valdivia, Héctor H., Niggli, Ernst
Publicado no J Gen Physiol (2019)

“... by using whole-cell patch–clamp recordings and confocal Ca(2+) imaging during β-ARs stimulation...”
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Macrophage-dependent impairment of α(2)-adrenergic autoreceptor inhibition of Ca(2+) channels in sympathetic neurons from DOCA-salt but not high-fat diet-induced hypertensive rats

Por Mui, Ryan K., Fernandes, Roxanne N., Garver, Hannah G., Van Rooijen, Nico, Galligan, James J.
Publicado no Am J Physiol Heart Circ Physiol (2018)

“... chemoattractant protein-1 and tumor necrosis factor-α, and impaired α(2)AR-mediated inhibition of Ca(2+) currents...”
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β(3)-Adrenoceptor activation relieves oxidative inhibition of the cardiac Na(+)-K(+) pump in hyperglycemia induced by insulin receptor blockade

Por Karimi Galougahi, Keyvan, Liu, Chia-Chi, Garcia, Alvaro, Fry, Natasha A., Hamilton, Elisha J., Figtree, Gemma A., Rasmussen, Helge H.
Publicado no Am J Physiol Cell Physiol (2015)

“...(+) pump β(1)-subunit, which may reflect facilitation of deglutathionylation. In vivo β(3)-AR activation...”
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Calcium release via activation of presynaptic IP3 receptors contributes to kainate-induced IPSC facilitation in rat neocortex

Por Mathew, Seena S., Hablitz, John J.
Publicado em 2008

“... cells using whole cell patch clamp techniques. KA produced an increase in evoked IPSC amplitude at low...”
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Flavan-3-ol esters: new agents for exploring modulatory sites on GABA(A) receptors

Por Fernandez, Sebastian P, Karim, Nasiara, Mewett, Kenneth N, Chebib, Mary, Johnston, Graham AR, Hanrahan, Jane R
Publicado em 2012

“... these agents. EXPERIMENTAL APPROACH: Using two-electrode voltage clamp electrophysiological recordings...”
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