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Calcium release via activation of presynaptic IP3 receptors contributes to kainate-induced IPSC facilitation in rat neocortex

We examined the mechanisms of kainate (KA) induced modulation of GABA release in rat prefrontal cortex. Pharmacologically isolated IPSCs were recorded from visually identified layer II/III pyramidal cells using whole cell patch clamp techniques. KA produced an increase in evoked IPSC amplitude at lo...

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Detalhes bibliográficos
Main Authors: Mathew, Seena S., Hablitz, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580077/
https://ncbi.nlm.nih.gov/pubmed/18508095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.05.005
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