The A(3) adenosine receptor agonist CP-532,903 protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP sensitive potassium channel

We examined the cardioprotective profile of the new A(3) adenosine receptor (AR) agonist CP-532,903 in an in vivo mouse model of infarction and an isolated heart model of global ischemia/reperfusion injury. In radioligand binding and cAMP accumulation assays using HEK 293 cells expressing recombinan...

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Autori principali: Wan, Tina C., Ge, Zhi-Dong, Tampo, Akihito, Mio, Yasushi, Bienengraeber, Martin W., Tracey, W. Ross, Gross, Garrett J., Kwok, Wai-Meng, Auchampach, John A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435594/
https://ncbi.nlm.nih.gov/pubmed/17906066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.127480
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