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Age-related Attenuation of Isoflurane Preconditioning in Human Atrial Cardiomyocytes: Roles for Mitochondrial Respiration and Sarcolemmal Adenosine Triphosphate-sensitive Potassium Channel Activity

BACKGROUND: Clinical trials suggest that anesthetic-induced preconditioning (APC) produces cardioprotection in humans, but the mechanisms of APC and significance of aging for APC in humans are not well understood. Here, the impact of age on the role of two major effectors of APC, mitochondria and sa...

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Detalhes bibliográficos
Main Authors: Mio, Yasushi, Bienengraeber, Martin W., Marinovic, Jasna, Gutterman, David D., Rakic, Mladen, Bosnjak, Zeljko J., Stadnicka, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697447/
https://ncbi.nlm.nih.gov/pubmed/18362592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318167af2d
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