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Preconditioning by isoflurane elicits mitochondrial protective mechanisms independent of sarcolemmal K(ATP) channel in mouse cardiomyocytes

Cardiac mitochondria and the sarcolemmal (sarc)K(ATP) channels contribute to cardioprotective signaling of anesthetic-induced preconditioning (APC). Changes in mitochondrial bioenergetics influence the sarcK(ATP) channel function, but whether this channel has impacts on mitochondria is uncertain. We...

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Bibliographic Details
Main Authors: Muravyeva, Maria, Sedlic, Filip, Dolan, Nicholas, Bosnjak, Zeljko J, Stadnicka, Anna
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648596/
https://ncbi.nlm.nih.gov/pubmed/23318991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e318285f55b
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