Resultados da pesquisa - (( j fauna congo rare non ) OR ((( 1 dna clamp can non ) OR ( j e (cole OR core) can ngos ))))*

1

Reverse transcriptases can clamp together nucleic acids strands with two complementary bases at their 3′-termini for initiating DNA synthesis

Por Oz-Gleenberg, Iris, Herschhorn, Alon, Hizi, Amnon
Publicado em 2011

“... one C or G. This RT-induced strand ‘clamping’ activity promotes RT-directed DNA synthesis...”
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2

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Data on the target search by a single protein on DNA measured with ultrafast force-clamp spectroscopy

Por Carina Monico, Alessia Tempestini, Lucia Gardini, Francesco Saverio Pavone, Marco Capitanio
Publicado em 2019-06-01

“... to few tens of base pairs amongst the millions of non-specific chromosomal DNA has been puzzling...”
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3

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RNA polymerase clamp conformational dynamics: long-lived states and modulation by crowding, cations, and nonspecific DNA binding

Por Mazumder, Abhishek, Wang, Anna, Uhm, Heesoo, Ebright, Richard H, Kapanidis, Achillefs N
Publicado no Nucleic Acids Res (2021)

“... to non-specific DNA predominantly exhibits a closed clamp conformation. Our results raise the possibility...”
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4

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The phosphate clamp: sequence selective nucleic acid binding profiles and conformational induction of endonuclease inhibition by cationic Triplatin complexes

Por Prisecaru, Andreea, Molphy, Zara, Kipping, Ralph G., Peterson, Erica J., Qu, Yun, Kellett, Andrew, Farrell, Nicholas P.
Publicado no Nucleic Acids Res (2014)

“...(−1)). The phosphate clamp–DNA interactions result in condensation of superhelical and B-DNA...”
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5

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Data on the target search by a single protein on DNA measured with ultrafast force-clamp spectroscopy

Por Monico, Carina, Tempestini, Alessia, Gardini, Lucia, Pavone, Francesco Saverio, Capitanio, Marco
Publicado no Data Brief (2019)

“... to few tens of base pairs amongst the millions of non-specific chromosomal DNA has been puzzling...”
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DNA clamp function of the mono-ubiquitinated Fanconi Anemia ID complex

Por Wang, Renjing, Wang, Shengliu, Dhar, Ankita, Peralta, Christopher, Pavletich, Nikola P.
Publicado no Nature (2020)

“... branched DNA structures, becoming a sliding DNA clamp that can coordinate the subsequent repair reactions...”
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7

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A structure–function analysis of the yeast Elg1 protein reveals the importance of PCNA unloading in genome stability maintenance

Por Shemesh, Keren, Sebesta, Marek, Pacesa, Martin, Sau, Soumitra, Bronstein, Alex, Parnas, Oren, Liefshitz, Batia, Venclovas, Česlovas, Krejci, Lumir, Kupiec, Martin
Publicado no Nucleic Acids Res (2017)

“...The sliding clamp, PCNA, plays a central role in DNA replication and repair. In the moving...”
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8

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An N-terminal clamp restrains the motor domains of the bacterial transcription-repair coupling factor Mfd

Por Murphy, Michael N., Gong, Peng, Ralto, Kenneth, Manelyte, Laura, Savery, Nigel J., Theis, Karsten
Publicado em 2009

“... instrumental in recruiting DNA repair proteins (domains 1–3, MfdN), and a C-terminal part harboring motor...”
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9

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NDRG1 facilitates the replication and persistence of Kaposi’s sarcoma-associated herpesvirus by interacting with the DNA polymerase clamp PCNA

Por Zhang, Fang, Liang, Deguang, Lin, Xiaoxi, Zou, Zhe, Sun, Rui, Wang, Xing, Liang, Xiaozhen, Kaye, Kenneth M., Lan, Ke
Publicado no PLoS Pathog (2019)

“.... In present study, we found that N-Myc downstream regulated gene 1 (NDRG1), a cellular gene known to be non...”
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10

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Structure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1

Por Rappas, Mathieu, Oliver, Antony W., Pearl, Laurence H.
Publicado em 2011

“... by coupling binding of the 9-1-1 checkpoint clamp at sites of ssDNA, to activation of the ATR–ATRIP checkpoint...”
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11

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The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells

Por Bacquin, Agathe, Pouvelle, Caroline, Siaud, Nicolas, Perderiset, Mylène, Salomé-Desnoulez, Sophie, Tellier-Lebegue, Carine, Lopez, Bernard, Charbonnier, Jean-Baptiste, Kannouche, Patricia L.
Publicado em 2013

“... the degradation of FBH1 after DNA damage. Firstly, we found that the sliding clamp Proliferating Cell Nuclear...”
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The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic...

Por Gembka, Agnieszka, Toueille, Magali, Smirnova, Ekaterina, Poltz, Rainer, Ferrari, Elena, Villani, Giuseppe, Hübscher, Ulrich
Publicado em 2007

“... endonuclease 1 (Fen 1), DNA ligase I (Lig I) and the MutY homologue of Schizosaccharomyces pombe. In this work...”
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Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair

Por Liu, Jiaquan, Hanne, Jeungphill, Britton, Brooke M., Bennett, Jared, Kim, Daehyung, Lee, Jong-Bong, Fishel, Richard
Publicado no Nature (2016)

“...–EcMutH search complex illustrates how sequential stable sliding clamps can modulate one-dimensional...”
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14

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Diffusion of ring-shaped proteins along DNA: case study of sliding clamps

Por Daitchman, Dina, Greenblatt, Harry M, Levy, Yaakov
Publicado no Nucleic Acids Res (2018)

“... (i.e. ring) shape that topologically traps DNA, with this quality being essential to their function...”
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15

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Single strand transposition at the host replication fork

Por Lavatine, Laure, He, Susu, Caumont-Sarcos, Anne, Guynet, Catherine, Marty, Brigitte, Chandler, Mick, Ton-Hoang, Bao
Publicado no Nucleic Acids Res (2016)

“... fork targeting and analysed DNA-binding properties of the transposase which can assist localization...”
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16

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The phosphate clamp: a small and independent motif for nucleic acid backbone recognition

Por Komeda, Seiji, Moulaei, Tinoush, Chikuma, Masahiko, Odani, Akira, Kipping, Ralph, Farrell, Nicholas P., Williams, Loren Dean
Publicado em 2011

“...The 1.7 Å X-ray crystal structure of the B-DNA dodecamer, [d(CGCGAATTCGCG)](2) (DDD)-bound non...”
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17

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PCNA stimulates catalysis by structure-specific nucleases using two distinct mechanisms: substrate targeting and catalytic step

Por Hutton, Richard D., Roberts, Jennifer A., Penedo, J. Carlos, White, Malcolm F.
Publicado em 2008

“...The sliding clamp Proliferating Cell Nuclear Antigen (PCNA) functions as a recruiter and organizer...”
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Detection of Plasma BRAF(V600E) Mutation Is Associated with Lung Metastasis in Papillary Thyroid Carcinomas

Por Kim, Bo Hyun, Kim, In Joo, Lee, Byung Joo, Lee, Jin Choon, Kim, In Suk, Kim, Seong-Jang, Kim, Won Jin, Jeon, Yun Kyung, Kim, Sang Soo, Kim, Yong Ki
Publicado no Yonsei Med J (2015)

“... were analyzed for BRAF(V600E) mutation using a peptide nucleic acid (PNA) clamp real-time polymerase...”
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mRNA expression and DNA methylation analysis of the inhibitory mechanism of H(2)O(2) on the proliferation of A549 cells

Por Li, Yepeng, Wei, Zhongheng, Huang, Shiqing, Yang, Bo
Publicado no Oncol Lett (2020)

“.... Oxidative stress and DNA methylation feature a common denominator: The one carbon cycle. To explore...”
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DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation

Por Guha, Minakshi, Castellanos-Rizaldos, Elena, Makrigiorgos, G. Mike
Publicado em 2013

“... T790M EGFR mutations from target DNA prior to implementing PNA-LNA PCR, a method that can detect 1...”
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