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DNA clamp function of the mono-ubiquitinated Fanconi Anemia ID complex
The FANCI-FANCD2 (ID) complex, mutated in the Fanconi Anemia (FA) cancer predisposition syndrome, is required for the repair of interstrand crosslinks (ICL) and related lesions(1). The FA pathway is activated when a replication fork stalls at an ICL(2), triggering the mono-ubiquitination of the ID c...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7398534/ https://ncbi.nlm.nih.gov/pubmed/32269332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2110-6 |
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