The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells

During replication, DNA damage can challenge replication fork progression and cell viability. Homologous Recombination (HR) and Translesion Synthesis (TLS) pathways appear as major players involved in the resumption and completion of DNA replication. How both pathways are coordinated in human cells...

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Detalhes bibliográficos
Main Authors: Bacquin, Agathe, Pouvelle, Caroline, Siaud, Nicolas, Perderiset, Mylène, Salomé-Desnoulez, Sophie, Tellier-Lebegue, Carine, Lopez, Bernard, Charbonnier, Jean-Baptiste, Kannouche, Patricia L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711418/
https://ncbi.nlm.nih.gov/pubmed/23677613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt397
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