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Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligase
Eukaryotic cell cycle transitions are driven by E3 ubiquitin ligases that catalyze the ubiquitylation and destruction of specific protein targets. For example, the anaphase-promoting complex/cyclosome (APC/C) promotes the exit from mitosis via destruction of securin and mitotic cyclins, whereas CRL1...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3182024/ https://ncbi.nlm.nih.gov/pubmed/21828267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2068611 |
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