PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4(Cdt2) ubiquitin ligase complex

The DNA polymerase delta processivity factor Proliferating Cell Nuclear Antigen (PCNA) promotes the DNA damage-induced degradation of the replication initiation factor Cdt1 via the CRL4(Cdt2) E3 ubiquitin ligase complex. Here we demonstrate that PCNA promotes the ubiquitylation and degradation of th...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Abbas, Tarek, Sivaprasad, Uma, Terai, Kenta, Amador, Virginia, Pagano, Michele, Dutta, Anindya
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2008
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546691/
https://ncbi.nlm.nih.gov/pubmed/18794347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1676108
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires