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PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4(Cdt2) ubiquitin ligase complex
The DNA polymerase delta processivity factor Proliferating Cell Nuclear Antigen (PCNA) promotes the DNA damage-induced degradation of the replication initiation factor Cdt1 via the CRL4(Cdt2) E3 ubiquitin ligase complex. Here we demonstrate that PCNA promotes the ubiquitylation and degradation of th...
Tallennettuna:
| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Cold Spring Harbor Laboratory Press
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2546691/ https://ncbi.nlm.nih.gov/pubmed/18794347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1676108 |
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