Docking of a specialized PIP box onto chromatin-bound PCNA creates a degron for the ubiquitin ligase CRL4(Cdt2)

Por Havens, Courtney G., Walter, Johannes C.
Publicado em 2009

Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligase

Por Havens, Courtney G., Walter, Johannes C.
Publicado em 2011

Regulation of Late G(1)/S Phase Transition and APC(Cdh1) by Reactive Oxygen Species

Por Havens, Courtney G., Ho, Alan, Yoshioka, Naohisa, Dowdy, Steven F.
Publicado em 2006

A genome wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction

Por Raman, Malavika, Havens, Courtney G., Walter, Johannes C., Harper, J. Wade
Publicado em 2011

Thymine DNA Glycosylase Is a CRL4(Cdt2) Substrate

Por Slenn, Tamara J., Morris, Benjamin, Havens, Courtney G., Freeman, Robert M., Takahashi, Tatsuro S., Walter, Johannes C.
Publicado em 2014

Direct Role for Proliferating Cell Nuclear Antigen in Substrate Recognition by the E3 Ubiquitin Ligase CRL4(Cdt2)

Por Havens, Courtney G., Shobnam, Nadia, Guarino, Estrella, Centore, Richard C., Zou, Lee, Kearsey, Stephen E., Walter, Johannes C.
Publicado em 2012

Ribonucleotide reductase activity is regulated by proliferating cell nuclear antigen (PCNA)

Por Salguero, Israel, Guarino, Estrella, Shepherd, Marianne, Deegan, Tom, Havens, Courtney G., MacNeill, Stuart A., Walter, Johannes C., Kearsey, Stephen E.
Publicado em 2012

CRL4(Cdt2)-Mediated Destruction of the Histone Methyltransferase Set8 Prevents Premature Chromatin Compaction in S Phase

Por Centore, Richard C., Havens, Courtney G., Manning, Amity L., Li, Ju-Mei, Flynn, Rachel Litman, Tse, Alice, Jin, Jianping, Dyson, Nicholas J., Walter, Johannes C., Zou, Lee
Publicado em 2010

Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase...

Por Gandhi, Anita K, Kang, Jian, Havens, Courtney G, Conklin, Thomas, Ning, Yuhong, Wu, Lei, Ito, Takumi, Ando, Hideki, Waldman, Michelle F, Thakurta, Anjan, Klippel, Anke, Handa, Hiroshi, Daniel, Thomas O, Schafer, Peter H, Chopra, Rajesh
Publicado no Br J Haematol (2014)

CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL

Por Hagner, Patrick R., Man, Hon-Wah, Fontanillo, Celia, Wang, Maria, Couto, Suzana, Breider, Mike, Bjorklund, Chad, Havens, Courtney G., Lu, Gang, Rychak, Emily, Raymon, Heather, Narla, Rama Krishna, Barnes, Leo, Khambatta, Gody, Chiu, Hsiling, Kosek, Jolanta, Kang, Jian, Amantangelo, Michael D., Waldman, Michelle, Lopez-Girona, Antonia, Cai, Ti, Pourdehnad, Michael, Trotter, Matthew, Daniel, Thomas O., Schafer, Peter H., Klippel, Anke, Thakurta, Anjan, Chopra, Rajesh, Gandhi, Anita K.
Publicado no Blood (2015)