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1
Por Christopher S. Koivisto, Melodie Parrish, Santosh B. Bonala, Soo Ngoi, Adrian Torres, James Gallagher, Rebekah Sanchez-Hodge, Victor Zeinner, Georges J. Nahhas, Bei Liu, David E. Cohn, Floor J. Backes, Paul J. Goodfellow, Helen M. Chamberlin, Gustavo Leone
Publicado em 2020-10-01
Assuntos:
“...Preclinical drug evaluation...”Publicado em 2020-10-01
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2
Por Spagnuolo, Vincenzo, Galli, Laura, Poli, Andrea, Salpietro, Stefania, Gianotti, Nicola, Piatti, Piermarco, Cossarini, Francesca, Vinci, Concetta, Carini, Elisabetta, Lazzarin, Adriano, Castagna, Antonella
Publicado no BMC Infect Dis (2017)
“... investigated the associations of statin use and exposure to antiretroviral drugs with type 2 DM onset in a...”Publicado no BMC Infect Dis (2017)
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3
Por Elisa S. Roesti, Christina N. Boyle, Daniel T. Zeman, Marcos Sande-Melon, Federico Storni, Gustavo Cabral-Miranda, Alexander Knuth, Thomas A. Lutz, Monique Vogel, Martin F. Bachmann
Publicado em 2020-03-01
“...Type 2 diabetes mellitus (T2DM) is a chronic progressive disease characterized by insulin...”Publicado em 2020-03-01
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4
Por Liu, Jin, Bradley, Ryan, Eckmann, David M., Ayyaswamy, Portonovo S., Radhakrishnan, Ravi
Publicado em 2011
“... and diagnostic applications. In this paper we review the recent development of models at multiple length and time...”Publicado em 2011
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5
Por Zhang, Xiaolin, Zheng, Tihua, Sang, Lu, Apisa, Luke, Zhao, Hongchun, Fu, Fenghua, Wang, Qingzhu, Wang, Yanfei, Zheng, Qing Yin
Publicado no Infect Genet Evol (2015)
“... animal model. Peptidoglycan-polysaccharide (PGPS) of the bacterial cell wall can induce inflammation...”Publicado no Infect Genet Evol (2015)
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6
Por Hoffman-Luca, C. Gianna, Yang, Chao-Yie, Lu, Jianfeng, Ziazadeh, Daniel, McEachern, Donna, Debussche, Laurent, Wang, Shaomeng
Publicado no PLoS One (2015)
“.... Computational modeling suggested that a p53 tetramer containing two wild-type p53 molecules and two C176F...”Publicado no PLoS One (2015)
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7
Por De Rose, Francescaelena, Marotta, Roberto, Poddighe, Simone, Talani, Giuseppe, Catelani, Tiziano, Setzu, Maria Dolores, Solla, Paolo, Marrosu, Francesco, Sanna, Enrico, Kasture, Sanjay, Acquas, Elio, Liscia, Anna
Publicado no PLoS One (2016)
“... methanolic extract (Wse) on the LRRK2 loss-of-function Dm model of PD. To this end mutant and wild type (WT...”Publicado no PLoS One (2016)
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8
Por Henrichfreise, Beate, Wiegand, Irith, Luhmer-Becker, Ingeborg, Wiedemann, Bernd
Publicado em 2007
“... and the development of mutation-mediated resistance in wild-type and hypermutable Pseudomonas aeruginosa strains. We...”Publicado em 2007
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9
Por Lyzogubov, Valeriy V., Bora, Puran S., Wu, Xiaobo, Horn, Leah E., de Roque, Ryan, Rudolf, Xeniya V., Atkinson, John P., Bora, Nalini S.
Publicado no Am J Pathol (2016)
“... should provide valuable insights into pathogenesis and a test model system for novel drug targets. More...”Publicado no Am J Pathol (2016)
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10
Por Kobet, Robert A., Pan, Xiaoping, Zhang, Baohong, Pak, Stephen C., Asch, Adam S., Lee, Myon-Hee
Publicado em 2014
“... provides an exceptional model for genetic, molecular, and cellular analysis of human disease-related genes...”Publicado em 2014
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11
“... model for nonobese type 2 diabetes. Metformin (350 mg/kg/day) was given to SDT rats for 17 weeks. Blood...”
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12
Por Qi-Liang Mao-Ying, Annemieke Kavelaars, Karen Krukowski, Xiao-Jiao Huo, Wenjun Zhou, Theodore J Price, Charles Cleeland, Cobi J Heijnen
Publicado em 2014-01-01
“... that metformin protects against pain and loss of tactile function in a mouse model of CIPN. The finding...”Publicado em 2014-01-01
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13
Por Mao-Ying, Qi-Liang, Kavelaars, Annemieke, Krukowski, Karen, Huo, Xiao-Jiao, Zhou, Wenjun, Price, Theodore J., Cleeland, Charles, Heijnen, Cobi J.
Publicado em 2014
“... that metformin protects against pain and loss of tactile function in a mouse model of CIPN. The finding...”Publicado em 2014
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14
Preclinical assessments of the MEK inhibitor PD-0325901 in a mouse model of neurofibromatosis type 1
Por Jousma, Edwin, Rizvi, Tilat A., Wu, Jianqiang, Janhofer, David, Dombi, Eva, Dunn, Richard S., Kim, Mi-Ok, Masters, Andrea R., Jones, David R., Cripe, Timothy P., Ratner, Nancy
Publicado no Pediatr Blood Cancer (2015)
“...BACKGROUND: Neurofibromatosis type 1 (NF1) is a genetic disorder that predisposes affected...”Publicado no Pediatr Blood Cancer (2015)
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15
Por Xia, Guangbin, Santostefano, Katherine, Hamazaki, Takashi, Liu, Jilin, Subramony, SH, Terada, Naohiro, Ashizawa, Tetsuo
Publicado em 2012
“... that hamper therapeutic development is lack of an ideal disease model. In this study, we have generated...”Publicado em 2012
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16
17
Por Ning-Ning Wang, Xiang-Gui Wang, Guo-Li Xiong, Zi-Yi Yang, Ai-Ping Lu, Xiang Chen, Shao Liu, Ting-Jun Hou, Dong-Sheng Cao
Publicado em 2022-04-01
Assuntos:
“...Metabolic drug interaction...”Publicado em 2022-04-01
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18
“...-acetoxy-N-(4-(benzothiazol-2-yl)phenyl)hydroxylamine 8, a model metabolite of 2-(4-aminophenyl...”
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19
Por Dhaher, Roni, Damisah, Eyiyemisi C, Wang, Helen, Gruenbaum, Shaun, Ong, Caroline, Zaveri, Hitten P, Gruenbaum, Benjamin, Eid, Tore
Publicado em 2014
“... of the most severe type of seizures in the MSO model of MTLE. These results may have implications...”Publicado em 2014
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20
Por Monica G Risley, Stephanie P Kelly, Kailiang Jia, Brock Grill, Ken Dawson-Scully
Publicado em 2016-01-01
“...The microscopic nematode Caenorhabditis elegans has emerged as a valuable model for understanding...”Publicado em 2016-01-01
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