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Otitis media induced by peptidoglycan-polysaccharide (PGPS) in TLR2-deficient (Tlr2(−/−)) mice for developing drug therapy
BACKGROUND: Toll like receptor 2 (TLR2) signaling can regulate the pathogenesis of otitis media (OM). However, the precise role of TLR2 signaling in OM has not been clarified due to the lack of an optimal animal model. Peptidoglycan-polysaccharide (PGPS) of the bacterial cell wall can induce inflamm...
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| Publicado no: | Infect Genet Evol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617670/ https://ncbi.nlm.nih.gov/pubmed/26296608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2015.08.019 |
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