Otitis media induced by peptidoglycan-polysaccharide (PGPS) in TLR2-deficient (Tlr2(−/−)) mice for developing drug therapy

BACKGROUND: Toll like receptor 2 (TLR2) signaling can regulate the pathogenesis of otitis media (OM). However, the precise role of TLR2 signaling in OM has not been clarified due to the lack of an optimal animal model. Peptidoglycan-polysaccharide (PGPS) of the bacterial cell wall can induce inflamm...

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Publicado en:Infect Genet Evol
Main Authors: Zhang, Xiaolin, Zheng, Tihua, Sang, Lu, Apisa, Luke, Zhao, Hongchun, Fu, Fenghua, Wang, Qingzhu, Wang, Yanfei, Zheng, Qing Yin
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617670/
https://ncbi.nlm.nih.gov/pubmed/26296608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2015.08.019
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