Resultados da pesquisa - (( drug de ((novel ther) OR (level theory)) ) OR ( drug doses ((novel ther) OR (level theory)) ))

Pesquisas alternativas:
level theory » legal theory (Expandir a Pesquisa), model theory (Expandir a Pesquisa)
novel ther » novel ether (Expandir a Pesquisa), novel thr (Expandir a Pesquisa), novel theory (Expandir a Pesquisa)
drug doses » drug dose (Expandir a Pesquisa), drug disease (Expandir a Pesquisa)
drug de » drug dose (Expandir a Pesquisa), drug dna (Expandir a Pesquisa)

1

Bioengineering Novel Chimeric microRNA-34a for Prodrug Cancer Therapy: High-Yield Expression and Purification, and Structural and Functional Characterization

Bioengineering Novel Chimeric microRNA-34a for Prodrug Cancer Therapy: High-Yield Expression and Purification, and Structural and Functional Characterization

Por Wang, Wei-Peng, Ho, Pui Yan, Chen, Qiu-Xia, Addepalli, Balasubrahmanyam, Limbach, Patrick A., Li, Mei-Mei, Wu, Wen-Juan, Jilek, Joseph L., Qiu, Jing-Xin, Zhang, Hong-Jian, Li, Tianhong, Wun, Theodore, White, Ralph DeVere, Lam, Kit S., Yu, Ai-Ming
Publicado no J Pharmacol Exp Ther (2015)

Assuntos: “...Drug Discovery and Translational Medicine...”
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2

A criticism of the reductionist and holistic vision in the planning of drugs in biological, chemical and physical level

A criticism of the reductionist and holistic vision in the planning of drugs in biological, chemical and physical level

Por Daniel Augusto Barra de Oliveira, Edenilson dos Santos Niculau
Publicado no Eclética Química (2021)

Assuntos: “...Drug design...”
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3

Treatment of allergic rhinitis and urticaria: a review of the newest antihistamine drug bilastine

Treatment of allergic rhinitis and urticaria: a review of the newest antihistamine drug bilastine

Por Wang, Xue Yan, Lim-Jurado, Margaret, Prepageran, Narayanan, Tantilipikorn, Pongsakorn, Wang, De Yun
Publicado no Ther Clin Risk Manag (2016)

“... that it has very low potential for drug–drug interactions, and does not require dose adjustment in renal...”
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4

Network-Based Approaches in Drug Discovery and Early Development

Network-Based Approaches in Drug Discovery and Early Development

Por Harrold, JM, Ramanathan, M, Mager, DE
Publicado no Clin Pharmacol Ther (2013)

“...Identification of novel targets is a critical first step in the drug discovery and development...”
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5

Dose Titration Algorithm Tuning (DTAT) should supersede ‘the’ Maximum Tolerated Dose (MTD) in oncology dose-finding trials [version 2; referees: 2 approved, 1 approved with reservations]

Dose Titration Algorithm Tuning (DTAT) should supersede ‘the’ Maximum Tolerated Dose (MTD...

Por David C. Norris
Publicado em 2017-03-01

Assuntos: “...Theory & Simulation...”
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6

Stroke Prevention in Atrial Fibrillation: A Clinical Perspective on Trials of the Novel Oral Anticoagulants

Stroke Prevention in Atrial Fibrillation: A Clinical Perspective on Trials of the Novel Oral Anticoagulants

Por Morais, João, De Caterina, Raffaele
Publicado no Cardiovasc Drugs Ther (2016)

“... pharmacokinetics and pharmacodynamics, and they frequently interact with food and other drugs, requiring...”
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7

Novel Screening Assay for the Selective Detection of G-Protein-Coupled Receptor Heteromer Signaling

Novel Screening Assay for the Selective Detection of G-Protein-Coupled Receptor Heteromer Signaling

Por van Rijn, Richard M., Harvey, Jessica H., Brissett, Daniela I., DeFriel, Julia N., Whistler, Jennifer L.
Publicado em 2013

Assuntos: “...Drug Discovery and Translational Medicine...”
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8

Resolving anaphoras for the extraction of drug-drug interactions in pharmacological documents

Resolving anaphoras for the extraction of drug-drug interactions in pharmacological documents

Por Segura-Bedmar, Isabel, Crespo, Mario, de Pablo-Sánchez, César, Martínez, Paloma
Publicado em 2010

“..., it focuses on documents reflecting drug interactions. The Centering Theory has proved being effective...”
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9

Personalizing initial therapy in acute myeloid leukemia: incorporating novel agents into clinical practice

Personalizing initial therapy in acute myeloid leukemia: incorporating novel agents into clinical practice

Por DeStefano, Christin B., Hourigan, Christopher S.
Publicado no Ther Adv Hematol (2018)

“... for decades or less-intensive hypomethylating therapy. The year 2017, however, witnessed US Food and Drug...”
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10

Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection

Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection

Por da Silva, Cristiane França, Batista, Denise da Gama Jaén, de Araújo, Julianna Siciliano, Cunha-Junior, Edézio Ferreira, Stephens, Chad E, Banerjee, Moloy, Farahat, Abdelbasset A, Akay, Senol, Fisher, Mary K, Boykin, David W, Soeiro, Maria de Nazaré Correia
Publicado no Drug Des Devel Ther (2017)

“... against intracellular microorganisms. In the present study, three novel AIAs were evaluated in a mouse...”
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11

Nitric oxide in paediatric respiratory disorders: novel interventions to address associated vascular phenomena?

Nitric oxide in paediatric respiratory disorders: novel interventions to address associated vascular phenomena?

Por Akter, Farhana, Coghlan, Gerry, de Mel, Achala
Publicado no Ther Adv Cardiovasc Dis (2016)

“... is one of the limitations. There are significant developments in drug delivery methods and there is a...”
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12

Mechanisms of acquired resistance to androgen receptor targeting drugs in castration resistant prostate cancer

Mechanisms of acquired resistance to androgen receptor targeting drugs in castration resistant prostate cancer

Por Chism, David D., De Silva, Dinuka, Whang, Young E.
Publicado no Expert Rev Anticancer Ther (2014)

“... receptors such as glucocorticoid receptor may substitute for androgen receptor. Drugs with novel mechanisms...”
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13

A novel small-molecule inhibitor of HIV-1 entry

A novel small-molecule inhibitor of HIV-1 entry

Por Heredia, Alonso, Latinovic, Olga S, Barbault, Florent, de Leeuw, Erik PH
Publicado no Drug Des Devel Ther (2015)

“... options due to HIV-1 resistance, side effects, or drug costs. Further, it is likely that current drugs...”
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14

Modulation of Protein–Protein Interactions for the Development of Novel Therapeutics

Modulation of Protein–Protein Interactions for the Development of Novel Therapeutics

Por Petta, Ioanna, Lievens, Sam, Libert, Claude, Tavernier, Jan, De Bosscher, Karolien
Publicado no Mol Ther (2016)

“... to investigate the unexplored potential of PPIs in drug discovery is driven by the need to find novel therapeutic...”
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15

Understanding the within-host dynamics of influenza A virus: from theory to clinical implications

Understanding the within-host dynamics of influenza A virus: from theory to clinical implications

Por Hadjichrysanthou, Christoforos, Cauët, Emilie, Lawrence, Emma, Vegvari, Carolin, de Wolf, Frank, Anderson, Roy M.
Publicado no J R Soc Interface (2016)

“... immunotherapy and antiviral drugs for the treatment of infection at different times post infection. Through...”
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16

Novel small molecule EGFR inhibitors as candidate drugs in non-small cell lung cancer

Novel small molecule EGFR inhibitors as candidate drugs in non-small cell lung cancer

Por Berardi, Rossana, Santoni, Matteo, Morgese, Francesca, Ballatore, Zelmira, Savini, Agnese, Onofri, Azzurra, Mazzanti, Paola, Pistelli, Mirco, Pierantoni, Chiara, De Lisa, Mariagrazia, Caramanti, Miriam, Pagliaretta, Silvia, Pellei, Chiara, Cascinu, Stefano
Publicado em 2013

“...://www.clinicaltrials.gov), aimed to evaluate the efficacy and toxicity of combined approaches and to develop novel...”
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17

Pharmacological Treatment of Presbyopia by Novel Binocularly Instilled Eye Drops: A Pilot Study

Pharmacological Treatment of Presbyopia by Novel Binocularly Instilled Eye Drops: A Pilot Study

Por Renna, Antonio, Vejarano, L. Felipe, De la Cruz, Ernesto, Alió, Jorge L.
Publicado no Ophthalmol Ther (2016)

“...PURPOSE: The feasibility, in terms of safety and potential efficacy, of a new drug combination...”
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18

Microdose-induced Drug-DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice

Microdose-induced Drug-DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice

Por Zimmermann, Maike, Wang, Si-Si, Zhang, Hongyong, Lin, Tzu-yin, Malfatti, Michael, Haack, Kurt, Ognibene, Ted, Yang, Hongyuan, Airhart, Susan, Turteltaub, Kenneth W., Cimino, George D., Tepper, Clifford G., Drakaki, Alexandra, Chamie, Karim, de Vere White, Ralph, Pan, Chong-xian, Henderson, Paul T.
Publicado no Mol Cancer Ther (2016)

“... to test the possibility that another drug in the regimen could cause a response. The mice were dosed...”
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19

Clinical performance of a novel ultrathin strut, low-dose, sirolimus-eluting stent with abluminal-only biodegradable polymeric coating for patients undergoing percutaneous coronary intervention in the daily practice

Clinical performance of a novel ultrathin strut, low-dose, sirolimus-eluting stent with abluminal...

Por Prado, Guy F. A., Ribeiro, Expedito E., Melo, Pedro H. M. C., Pinton, Fabio A., Esteves-Filho, Antonio, Takimura, Celso K., Mariani, Jose, Kajita, Luiz J., Marchiori, Gilberto, Araripe Falcao, Breno de Alencar, Galon, Micheli Z., Soares, Paulo R., Zalc, Silvio, Lemos, Pedro A.
Publicado no Cardiovasc Diagn Ther (2015)

“... of a busy catheterization laboratory, of a novel drug-eluting stent (DES) built with an ultra-thin...”
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20

Golimumab: A Novel Anti-Tumor Necrosis Factor

Golimumab: A Novel Anti-Tumor Necrosis Factor

Por Rossini, Maurizio, De Vita, Salvatore, Ferri, Clodoveo, Govoni, Marcello, Paolazzi, Giuseppe, Salvarani, Carlo, Adami, Silvano
Publicado em 2013

“... factor (TNF) administered monthly by subcutaneous injection. It is approved by the US Food and Drug...”
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