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Mechanisms of acquired resistance to androgen receptor targeting drugs in castration resistant prostate cancer

After initial response to androgen receptor targeting drugs abiraterone or enzalutamide, most patients develop progressive disease and therefore, castration resistant prostate cancer (CRPC) remains a terminal disease. Multiple mechanisms underlying acquired resistance have been postulated. Intratumo...

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Detalhes bibliográficos
Publicado no:Expert Rev Anticancer Ther
Main Authors: Chism, David D., De Silva, Dinuka, Whang, Young E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221359/
https://ncbi.nlm.nih.gov/pubmed/24927631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737140.2014.928594
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