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Mechanisms of acquired resistance to androgen receptor targeting drugs in castration resistant prostate cancer

After initial response to androgen receptor targeting drugs abiraterone or enzalutamide, most patients develop progressive disease and therefore, castration resistant prostate cancer (CRPC) remains a terminal disease. Multiple mechanisms underlying acquired resistance have been postulated. Intratumo...

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Pubblicato in:Expert Rev Anticancer Ther
Autori principali: Chism, David D., De Silva, Dinuka, Whang, Young E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221359/
https://ncbi.nlm.nih.gov/pubmed/24927631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737140.2014.928594
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