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Modulation of Protein–Protein Interactions for the Development of Novel Therapeutics

Protein–protein interactions (PPIs) underlie most biological processes. An increasing interest to investigate the unexplored potential of PPIs in drug discovery is driven by the need to find novel therapeutic targets for a whole range of diseases with a high unmet medical need. To date, PPI inhibiti...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Petta, Ioanna, Lievens, Sam, Libert, Claude, Tavernier, Jan, De Bosscher, Karolien
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886928/
https://ncbi.nlm.nih.gov/pubmed/26675501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.214
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