Modulation of Protein–Protein Interactions for the Development of Novel Therapeutics

Protein–protein interactions (PPIs) underlie most biological processes. An increasing interest to investigate the unexplored potential of PPIs in drug discovery is driven by the need to find novel therapeutic targets for a whole range of diseases with a high unmet medical need. To date, PPI inhibiti...

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Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Petta, Ioanna, Lievens, Sam, Libert, Claude, Tavernier, Jan, De Bosscher, Karolien
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886928/
https://ncbi.nlm.nih.gov/pubmed/26675501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.214
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