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Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp.
Reverse transcriptases can clamp together nucleic acids strands with two complementary bases at their 3′-termini for initiating DNA synthesis

The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks
DNA clamp function of the mono-ubiquitinated Fanconi Anemia ID complex

Sequence specificity at targeting double-stranded DNA with a γ-PNA oligomer modified with guanidinium G-clamp nucleobases
Replicative DNA Polymerases

NDRG1 facilitates the replication and persistence of Kaposi’s sarcoma-associated herpesvirus by interacting with the DNA polymerase clamp PCNA
The Main Role of Srs2 in DNA Repair Depends on Its Helicase Activity, Rather than on Its Interactions with PCNA or Rad51

Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy
Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy

Identification of deubiquitinase targets of isothiocyanates using SILAC-assisted quantitative mass spectrometry
PCNA stimulates catalysis by structure-specific nucleases using two distinct mechanisms: substrate targeting and catalytic step

Cdt1 revisited: complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells
Direct inhibition by cannabinoids of human 5-HT(3A) receptors: probable involvement of an allosteric modulatory site

Phylogeny and character evolution in the Dacrymycetes, and systematics of Unilacrymaceae and Dacryonaemataceae fam. nov.
Thermodynamic determination of the Na+: glucose coupling ratio for the human SGLT1 cotransporter.

Resurgent and Gating Pore Currents Induced by De Novo SCN2A Epilepsy Mutations
Influenza D virus M2 protein exhibits ion channel activity in Xenopus laevis oocytes

Low-frequency pulsed electromagnetic field pretreated bone marrow-derived mesenchymal stem cells promote the regeneration of crush-injured rat mental nerve
Single-molecule analysis of the E. coli replisome and use of clamps to bypass replication barriers

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