Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy

BACKGROUND: DNA polymerase D (PolD) is the representative member of the D family of DNA polymerases. It is an archaea-specific DNA polymerase required for replication and unrelated to other known DNA polymerases. PolD consists of a heterodimer of two subunits, DP1 and DP2, which contain catalytic si...

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Veröffentlicht in:BMC Biol
Hauptverfasser: Mayanagi, Kouta, Oki, Keisuke, Miyazaki, Naoyuki, Ishino, Sonoko, Yamagami, Takeshi, Morikawa, Kosuke, Iwasaki, Kenji, Kohda, Daisuke, Shirai, Tsuyoshi, Ishino, Yoshizumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594292/
https://ncbi.nlm.nih.gov/pubmed/33115459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00889-y
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