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Mechanism of replication machinery assembly as revealed by the DNA ligase–PCNA–DNA complex architecture

The 3D structure of the ternary complex, consisting of DNA ligase, the proliferating cell nuclear antigen (PCNA) clamp, and DNA, was investigated by single-particle analysis. This report presents the structural view, where the crescent-shaped DNA ligase with 3 distinct domains surrounds the central...

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Main Authors: Mayanagi, Kouta, Kiyonari, Shinichi, Saito, Mihoko, Shirai, Tsuyoshi, Ishino, Yoshizumi, Morikawa, Kosuke
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660782/
https://ncbi.nlm.nih.gov/pubmed/19255439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811196106
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