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Mechanism of replication machinery assembly as revealed by the DNA ligase–PCNA–DNA complex architecture
The 3D structure of the ternary complex, consisting of DNA ligase, the proliferating cell nuclear antigen (PCNA) clamp, and DNA, was investigated by single-particle analysis. This report presents the structural view, where the crescent-shaped DNA ligase with 3 distinct domains surrounds the central...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660782/ https://ncbi.nlm.nih.gov/pubmed/19255439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811196106 |
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