Nilotinib in patients with systemic mastocytosis: analysis of the phase 2, open-label, single-arm nilotinib registration study

Por Hochhaus, Andreas, Baccarani, Michele, Giles, Francis J., le Coutre, Philipp D., Müller, Martin C., Reiter, Andreas, Santanastasio, Helene, Leung, Mimi, Novick, Steven, Kantarjian, Hagop M.
Publicado no J Cancer Res Clin Oncol (2015)

A combined phase I and II open label study on the effects of a seaweed extract nutrient complex on osteoarthritis

Por Myers, Stephen P, O’Connor, Joan, Fitton, J Helen, Brooks, Lyndon, Rolfe, Margaret, Connellan, Paul, Wohlmuth, Hans, Cheras, Phil A, Morris, Carol
Publicado em 2010

The Molecular Mechanism by which PIP(2) Opens the Intracellular G-Loop Gate of a Kir3.1 Channel

Por Meng, Xuan-Yu, Zhang, Hong-Xing, Logothetis, Diomedes E., Cui, Meng
Publicado em 2012

Effects of food on the bioavailability of gepirone from extended-release tablets in humans: results of two open-label crossover studies()

Por Fabre, Louis F, Timmer, Cees J
Publicado em 2003

Double-stranded DNA translocase activity of transcription factor TFIIH and the mechanism of RNA polymerase II open complex formation

Por Fishburn, James, Tomko, Eric, Galburt, Eric, Hahn, Steven
Publicado no Proc Natl Acad Sci U S A (2015)

Adjacent channelrhodopsin-2 residues within transmembranes 2 and 7 regulate cation selectivity and distribution of the two open states

Por Richards, Ryan, Dempski, Robert E.
Publicado no J Biol Chem (2017)

Treatment of Disfiguring Cutaneous Lesions in Neurofibromatosis-1 with Everolimus: A Phase II, Open-Label, Single-Arm Trial

Por Slopis, John M., Arevalo, Octavio, Bell, Cynthia S., Hebert, Adelaide A., Northrup, Hope, Riascos, Roy F., Samuels, Joshua A., Smith, Keri C., Tate, Patti, Koenig, Mary Kay
Publicado no Drugs R D (2018)

Ecological traits drive genetic structuring in two open‐habitat birds from the morphologically cryptic genus Elaenia (Aves: Tyrannidae)

Por Eliane L. de Freitas, Leonardo Campagna, Bronwyn Butcher, Irby Lovette, Renato Caparroz
Publicado em 2022-04-01

Open reduction and internal fixation of Gustilo type-I and type-II open pilon fractures using a lateral approach

Por Chuanzhen Hu, Weiyi Zhu, Kapil Chahal, Nan Zhu, Wang Fang, Juehua Jing, Junfeng Zhan
Publicado em 2019-07-01

Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames.

Por Ustav, M, Stenlund, A
Publicado em 1991

Comparisons of three technics for femoral-popliteal arterial reconstruction, 1. vein bypass, 2. open endarterectomy, 3. semiclosed endarterectomy.

Por Imparato, A M, Bracco, A, Kim, G E
Publicado em 1973

Ca(2+)-Calmodulin Increases RyR2 Open Probability yet Reduces Ryanoid Association with RyR2

Por Sigalas, Charalambos, Mayo-Martin, Maria Belen, Jane, David E., Sitsapesan, Rebecca
Publicado em 2009

Phase II Open-Label Study to Assess Efficacy and Safety of Lenalidomide in Combination with Cetuximab in KRAS-Mutant Metastatic Colorectal Cancer

Por Siena, Salvatore, Van Cutsem, Eric, Li, Mingyu, Jungnelius, Ulf, Romano, Alfredo, Beck, Robert, Bencardino, Katia, Elez, Maria Elena, Prenen, Hans, Sanchis, Mireia, Sartore-Bianchi, Andrea, Tejpar, Sabine, Gandhi, Anita, Shi, Tao, Tabernero, Josep
Publicado em 2013

A multi-institutional, phase II open-label study of ganitumab (AMG 479) in advanced carcinoid and pancreatic neuroendocrine tumors

Por Strosberg, J R, Chan, J A, Ryan, D P, Meyerhardt, J A, Fuchs, C S, Abrams, T, Regan, E, Brady, R, Weber, J, Campos, T, Kvols, L K, Kulke, M H
Publicado em 2013

Ibuprofen Sodium Is Absorbed Faster than Standard Ibuprofen Tablets: Results of Two Open-Label, Randomized, Crossover Pharmacokinetic Studies

Por Legg, Thomas J., Laurent, Aziz L., Leyva, Rina, Kellstein, David
Publicado no Drugs R D (2014)

Phase 2 open-label extention (OLE) study of patisiran, an investigational siRNA agent for familial amyloidotic polyneuropathy (FAP)

Por Adams, David, Suhr, Ole B, Conceicao, Isabel, Waddington-Cruz, Marcia, Schmidt, Hartmut, Buades, Juan, Campistol, Josep, Coehlo, Teresa
Publicado no Orphanet J Rare Dis (2015)

Phase 2, open-label extension (OLE) study of revusiran, an investigational RNAi therapeutic...

Por Gillmore, Julian D, Falk, Rodney H, Maurer, Mathew S, Hanna, Mazen, Karsten, Verena, Vest, John, Gollob, Jared, Hawkins, Philip N
Publicado no Orphanet J Rare Dis (2015)

An Engineered Version of Human PON2 Opens the Way to Understand the Role of Its Post-Translational Modifications in Modulating Catalytic Activity

Por Mandrich, Luigi, Cerreta, Mariangela, Manco, Giuseppe
Publicado no PLoS One (2015)

Combining two open source tools for neural computation (BioPatRec and Netlab) improves movement classification for prosthetic control

Por Prahm, Cosima, Eckstein, Korbinian, Ortiz-Catalan, Max, Dorffner, Georg, Kaniusas, Eugenijus, Aszmann, Oskar C.
Publicado no BMC Res Notes (2016)

A phase II open label trial evaluating safety and efficacy of a telomerase peptide vaccination in patients with advanced hepatocellular carcinoma

Por Greten, Tim F, Forner, Alejandro, Korangy, Firouzeh, N'Kontchou, Gisele, Barget, Nathalie, Ayuso, Carmen, Ormandy, Lars A, Manns, Michael P, Beaugrand, Michel, Bruix, Jordi
Publicado em 2010