Phase II Open-Label Study to Assess Efficacy and Safety of Lenalidomide in Combination with Cetuximab in KRAS-Mutant Metastatic Colorectal Cancer

This study aimed to assess the efficacy and safety of combination treatment with lenalidomide and cetuximab in KRAS-mutant metastatic colorectal cancer patients. This was a phase II multicenter, open-label trial comprising a safety lead-in phase (phase IIa) to determine the maximum tolerated dose, a...

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Detalhes bibliográficos
Main Authors: Siena, Salvatore, Van Cutsem, Eric, Li, Mingyu, Jungnelius, Ulf, Romano, Alfredo, Beck, Robert, Bencardino, Katia, Elez, Maria Elena, Prenen, Hans, Sanchis, Mireia, Sartore-Bianchi, Andrea, Tejpar, Sabine, Gandhi, Anita, Shi, Tao, Tabernero, Josep
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823943/
https://ncbi.nlm.nih.gov/pubmed/24244261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062264
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