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Adjacent channelrhodopsin-2 residues within transmembranes 2 and 7 regulate cation selectivity and distribution of the two open states

Channelrhodopsin-2 (ChR2) is a light-activated channel that can conduct cations of multiple valencies down the electrochemical gradient. Under continuous light exposure, ChR2 transitions from a high-conducting open state (O1) to a low-conducting open state (O2) with differing ion selectivity. The mo...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Richards, Ryan, Dempski, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418034/
https://ncbi.nlm.nih.gov/pubmed/28302720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770321
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