CpG Oligodeoxynucleotides and Interleukin-12 Improve the Efficacy of Mycobacterium bovis BCG Vaccination in Mice Challenged with M. tuberculosis

Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the only vaccine approved for prevention of tuberculosis. It has been postulated that serial passage of BCG over the years may have resulted in attenuation of its effectiveness. Because interleukin-12 (IL-12) and oligodeoxynucleotides (ODN) conta...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Infect Immun
Prif Awduron:	Freidag, Brenda L., Melton, Genevieve B., Collins, Frank, Klinman, Dennis M., Cheever, Allen, Stobie, Laura, Suen, Winnie, Seder, Robert A.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 2000
Pynciau:	Microbial Immunity and Vaccines
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97508/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10768993/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.2948-2953.2000
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