The Toll-like receptor ligand, CpG oligodeoxynucleotides, regulate proliferation and osteogenic differentiation of osteoblast

Abstract Background This study aimed to investigate the regulation of CpG oligodeoxynucleotides (ODNs) on proliferation and osteogenic differentiation of MC3T3 cells. Methods The laser co-focusing and flow cytometry assay were employed to detect cell uptake of CpG ODN 2006. Twelve ODNs were sythesiz...

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Hlavní autoři:	Wenwen Yu, Yi Zheng, Hongyan Li, Hongbing Lin, Zhen Chen, Yue Tian, Huishan Chen, Peipei Zhang, Xiaowei Xu, Yuqin Shen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2020-08-01
Edice:	Journal of Orthopaedic Surgery and Research
Témata:	Periodontitis CpG ODN Osteoblast Proliferation Differentiation
On-line přístup:	http://link.springer.com/article/10.1186/s13018-020-01844-x
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