CpG Oligodeoxynucleotides and Interleukin-12 Improve the Efficacy of Mycobacterium bovis BCG Vaccination in Mice Challenged with M. tuberculosis

Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the only vaccine approved for prevention of tuberculosis. It has been postulated that serial passage of BCG over the years may have resulted in attenuation of its effectiveness. Because interleukin-12 (IL-12) and oligodeoxynucleotides (ODN) conta...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Freidag, Brenda L., Melton, Genevieve B., Collins, Frank, Klinman, Dennis M., Cheever, Allen, Stobie, Laura, Suen, Winnie, Seder, Robert A.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2000
Fag:	Microbial Immunity and Vaccines
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97508/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10768993/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.2948-2953.2000
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